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High Purity Tranexamic Acid CAS 1197-18-8 from Reliable China Suppliers and Factory
Tranexamic acid, also called tranexamic acid, is a synthetic derivative of lysine with a similar structure to tyrosine. Confirmed by clinical trials, it is suitable for all types of skin and can remove pigmentation, whiten, and lighten spots, such as: pigmentation after sun exposure, dark spots (chloasma, freckles, senile lentils, etc.), sensitive skin, Acne and inflammation, post-operative care after laser, pulsed light treatment, etc. Therefore, tranexamic acid can be recommended for use in cosmetics such as creams, lotions, essences, lotions, and facial masks.
Clinical Overview
Tranexamic acid is a synthetic amino acid antifibrinolytic drug that can competitively inhibit the binding of lysine in fibrin to plasmin, thereby inhibiting the lysis of fibrin clots and producing hemostasis. It is mainly used clinically for various types of bleeding caused by hyperfibrinolysis.
Tranexamic acid Applications
1. Tranexamic acid is an anti-fibrinolytic drug, it can treat various acute and chronic bleeding and achieve hemostasis.
2. Tranexamic acid can reduce melanin production: It can directly compete with tyrosine in cells, inhibit the catalytic effect of tyrosine metabolism, and reduce melanin production.
3. Inhibit skin angiogenesis: It can directly compete with tyrosine in cells, inhibit the catalytic effect of tyrosine metabolism, and inhibit skin angiogenesis. This can reduce the number of blood vessels in and around chloasma lesions, reduce the occurrence of inflammatory reactions, and thereby reduce the continuous formation of chloasma.
4. Tranexamic acid can reduce the expression of pro-inflammatory cytokines and chemokines to exert anti-inflammatory effects, which can effectively prevent the occurrence of allergic reactions and reduce the formation of acne.
5. Tranexamic acid has Anti-aging and anti-photoaging properties. It enhances hyaluronic acid synthesis by increasing the number of epidermal cells, reduces the degradation of extracellular matrix in the dermis by blocking plasmin, and can reduce the levels of some oxidative substances in the blood to improve the natural aging of the skin. Improves UVB-induced photoaging by increasing mitochondrial biogenesis, regulating hormone secretion by increasing the expression of estrogen receptors on the surface of mast cells, and improving UVA-induced photoaging.
Tranexamic acid Specification
Hebei WeiBang Biotechnology Co., Ltd
Add: Yuhua West Road, Qiaoxi District, Shijiazhuang City, Hebei Province
| Product Name | Tranexamic acid | CAS No | 1197-18-8 |
| Production Date | 2023/12/01 | Report Date | 2023/12/01 |
| Quantity | 10,000KG | Test Date | 2023/12/01 |
| Batch No | WB20231201 | Shelf life | 2 years |
| Testing Items | Specification | ||
| Appearance | White crystal powder | ||
| Identification | IR | ||
| Loss on drying | ≤0.50% | ||
| pH | 7.0-8.0 | ||
| Assay | ≥99.0 | ||
| Sulphated ash | ≤0.10% | ||
| Related substance | Impurity A: ≤0.10% | ||
| Impurity B: ≤0.20% | |||
| Any other impurity: ≤0.10% | |||
| All other impurity: ≤0.20% | |||
| Chlorides | ≤140ppm | ||
| Total plate count | ≤1000cfu/g | ||
| Yeast & mould | ≤100cfu/g | ||
| Pb | ≤10mg/kg | ||
| As | ≤2mg/kg | ||
| Hg | ≤1mg/kg | ||
| Cd | ≤5mg/kg | ||
| Conclusion | Qualified | ||
Frequently Asked Questions
What are the primary cosmetic benefits of Tranexamic Acid?
Tranexamic Acid is suitable for all skin types. It is clinically proven to remove pigmentation, whiten the skin, and lighten dark spots such as chloasma, freckles, senile lentils, and sunspots. It also helps soothe sensitive skin, reduces acne inflammation, and supports skin recovery after laser or pulsed light treatments.
How does Tranexamic Acid reduce melanin and target dark spots?
It directly competes with tyrosine within skin cells, effectively inhibiting the catalytic processes of tyrosine metabolism. By doing so, it significantly reduces the overall production of melanin, preventing the formation of new dark spots and fading existing hyperpigmentation.
Can Tranexamic Acid help with skin redness and blood vessels?
Yes. Tranexamic Acid inhibits skin angiogenesis (the formation of new blood vessels) by competing with tyrosine. This action reduces the number of blood vessels in and around chloasma lesions, lowering inflammatory responses and preventing the continuous development of vascular-related skin discoloration.
Does Tranexamic Acid provide anti-aging and anti-photoaging benefits?
Yes, it has strong anti-aging properties. It enhances hyaluronic acid synthesis by increasing epidermal cell count, blocks plasmin to prevent the degradation of the dermal extracellular matrix, and improves UVB/UVA-induced photoaging. It also regulates hormone secretion via estrogen receptors on mast cells.
What is the clinical mechanism of Tranexamic Acid in medical use?
Clinically, Tranexamic Acid is an antifibrinolytic drug. It competitively inhibits the binding of lysine in fibrin to plasmin. This action stops the breakdown of fibrin clots, thereby promoting hemostasis and stopping various types of bleeding caused by hyperfibrinolysis.
What are the quality specifications of Hebei WeiBang's Tranexamic Acid?
Hebei WeiBang's Tranexamic Acid (CAS 1197-18-8) is a highly pure white crystal powder with an assay purity of ≥99.0%. It features a pH range of 7.0-8.0, loss on drying of ≤0.50%, and complies with strict heavy metal limits (Pb ≤10mg/kg, As ≤2mg/kg) ensuring a fully qualified and stable product.