High Purity Tranexamic Acid CAS 1197-18-8 from China Suppliers and Factory for Pharmaceutical Applications
Tranexamic acid, also called tranexamic acid, is a synthetic derivative of lysine with a similar structure to tyrosine. Confirmed by clinical trials, it is suitable for all types of skin and can remove pigmentation, whiten, and lighten spots, such as: pigmentation after sun exposure, dark spots (chloasma, freckles, senile lentils, etc.), sensitive skin, Acne and inflammation, post-operative care after laser, pulsed light treatment, etc. Therefore, tranexamic acid can be recommended for use in cosmetics such as creams, lotions, essences, lotions, and facial masks.
Tranexamic acid is a synthetic amino acid antifibrinolytic drug that can competitively inhibit the binding of lysine in fibrin to plasmin, thereby inhibiting the lysis of fibrin clots and producing hemostasis. It is mainly used clinically for various types of bleeding caused by hyperfibrinolysis.
Tranexamic acid Applications
1. Anti-Fibrinolytic Drug: It can treat various acute and chronic bleeding and achieve hemostasis.
2. Reduces Melanin Production: It can directly compete with tyrosine in cells, inhibit the catalytic effect of tyrosine metabolism, and reduce melanin production.
3. Inhibit Angiogenesis: It can directly compete with tyrosine in cells, inhibit the catalytic effect of tyrosine metabolism, and inhibit skin angiogenesis. This can reduce the number of blood vessels in and around chloasma lesions, reduce the occurrence of inflammatory reactions, and thereby reduce the continuous formation of chloasma.
4. Anti-Inflammatory Action: Tranexamic acid can reduce the expression of pro-inflammatory cytokines and chemokines to exert anti-inflammatory effects, which can effectively prevent the occurrence of allergic reactions and reduce the formation of acne.
5. Anti-Aging & Anti-Photoaging: It enhances hyaluronic acid synthesis by increasing the number of epidermal cells, reduces the degradation of extracellular matrix in the dermis by blocking plasmin, and can reduce the levels of some oxidative substances in the blood to improve the natural aging of the skin. Improves UVB-induced photoaging by increasing mitochondrial biogenesis, regulating hormone secretion by increasing the expression of estrogen receptors on the surface of mast cells, and improving UVA-induced photoaging.
Tranexamic acid Specification
Hebei WeiBang Biotechnology Co., Ltd
Add: Yuhua West Road, Qiaoxi District, Shijiazhuang City, Hebei Province
| Product Name | Tranexamic acid | CAS No | 1197-18-8 |
| Production Date | 2023/12/01 | Report Date | 2023/12/01 |
| Quantity | 10,000KG | Test Date | 2023/12/01 |
| Batch No | WB20231201 | Shelf life | 2 years |
| Testing Items | Specification | ||
| Appearance | White crystal powder | ||
| Identification | IR | ||
| Loss on drying | ≤0.50% | ||
| pH | 7.0-8.0 | ||
| Assay | ≥99.0 | ||
| Sulphated ash | ≤0.10% | ||
| Related substance | Impurity A: ≤0.10% | ||
| Impurity B: ≤0.20% | |||
| Any other impurity: ≤0.10% | |||
| All other impurity: ≤0.20% | |||
| Chlorides | ≤140ppm | ||
| Total plate count | ≤1000cfu/g | ||
| Yeast & mould | ≤100cfu/g | ||
| Pb | ≤10mg/kg | ||
| As | ≤2mg/kg | ||
| Hg | ≤1mg/kg | ||
| Cd | ≤5mg/kg | ||
| Conclusion | Qualified | ||
Frequently Asked Questions (FAQ)
What is Tranexamic Acid and how does it function in skincare?
Tranexamic acid is a synthetic derivative of lysine with a structure similar to tyrosine. In skincare, it is suitable for all skin types and helps remove pigmentation, whiten the skin, and lighten spots caused by sun exposure, chloasma, freckles, and acne-induced inflammation.
How does Tranexamic Acid reduce melanin production?
It directly competes with tyrosine in cells, effectively inhibiting the catalytic effect of tyrosine metabolism. This action leads to a reduction in overall melanin production.
What are the benefits of Tranexamic Acid regarding anti-aging?
Tranexamic acid enhances hyaluronic acid synthesis by increasing epidermal cells and limits the degradation of the extracellular matrix in the dermis. It improves both UVB and UVA-induced photoaging and helps improve the natural aging processes of the skin.
Does Tranexamic Acid have anti-inflammatory properties?
Yes. It reduces the expression of pro-inflammatory cytokines and chemokines, helping prevent allergic reactions, reduce skin inflammation, and lower the formation of acne.
What is the clinical medical application of Tranexamic Acid?
Clinically, Tranexamic acid is a synthetic amino acid antifibrinolytic drug that competitively inhibits lysine binding in fibrin to plasmin, thereby stopping fibrin clot lysis and helping to control various acute and chronic bleedings caused by hyperfibrinolysis.
In what types of cosmetic products can Tranexamic Acid be formulated?
Because of its stability and skin benefits, it is highly recommended for use in cosmetic formulations such as creams, lotions, essences, skin lotions, and facial masks.